Absence of Soluble Leptin Receptor in Plasma fromdbPas/dbPas and Otherdb/db Mice
نویسندگان
چکیده
منابع مشابه
Developmental variations in plasma leptin, leptin soluble receptor and their molar ratio in healthy infants
BACKGROUND Leptin and its soluble receptor (sOB-R) are important to regulation of body composition but there are no data on the developmental variations in these plasma variables and their relationship with body composition measurements, METHODS Weight, length, and body composition (bone, fat and lean mass) by dual energy absorptiometry, and plasma variables were measured in healthy infants a...
متن کاملLeptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in US Women: A Prospective Study
From the 1 Departments of Nutrition, 2 Epidemiology, and 3 Environmental Health (Dr. Mantzoros), Harvard School of Public Health, Boston, MA 02115, USA; 4 Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; 5 General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Bosto...
متن کاملLeptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women
OBJECTIVE We prospectively examined plasma levels of leptin and soluble leptin receptor (sOB-R), as well as their interactions with other diabetes risk factors, in relation to type 2 diabetes to elucidate the complex relation between these two biomarkers and diabetes risk. RESEARCH DESIGN AND METHODS Of 32,826 Nurses' Health Study participants who provided blood samples during 1989-1990, 1,05...
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background: leptin plays a key role in the regulation of energy expenditure and is known to circulate in both free and bound forms. soluble leptin receptor (sob-r) is a unique circulating form of leptin receptor that can bind to leptin. leptin and leptin receptor have been implicated in processes leading to breast cancer initiation and progression. our study was aimed to investigate the relatio...
متن کاملPlasma adiponectin and soluble leptin receptor and risk of colorectal cancer: a prospective study.
Adipokines are adipocyte-secreted hormones that may mediate the etiologic link between obesity and colorectal cancer; however, the evidence from large prospective studies is limited. We prospectively evaluated the association of plasma adiponectin and soluble leptin receptor (sOB-R) with colorectal cancer risk within the Nurses' Health Study (1990-2008) and the Health Professionals Follow-up St...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1998
ISSN: 0021-9258
DOI: 10.1074/jbc.273.16.10078